Optional Light Leans

• *Live* Red Sox v. Rangers F5 Over 4.5 (-140)
• Nationals F5 ML (+140)
• Marlins F5 ML (+120)
• Reds F5 ML (-120) ( -0.5 for odds )
• Rays F5 ML
• Athletics F5 +1.5 (-140) ( ML for odds )

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Pirates F5 ML (+100) ( light )

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Royals ML (-120) *Live* ( light )

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Take Braves v. Giants Over 8.5 *Live*

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⏰#2: Real-world implications of dialysis vs. medical management in older adults with CKD

🕓10-second takeaway
Choosing whether to start dialysis can be difficult for older adults with chronic kidney disease (CKD) because there is limited practical data to guide their decision-making. In this observational cohort study of older adults with CKD, early initiation of dialysis was associated with a very modest, statistically nonsignificant increase in survival compared to medical management alone, but it was also associated with significantly less time spent at home. Including this information in decision aids and shared decision-making conversations can help patients with CKD make choices that align with their personal values and health care goals.

🔹Original study
Montez-Rath ME, Thomas IC, Charu V, et al. Effect of starting dialysis versus continuing medical management on survival and home time in older adults with kidney failure: a target trial emulation study. Ann Intern Med, 2024. doi: 10.7326/M23-3028

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⏰#1: Liberal vs. restrictive transfusion strategy in traumatic brain injury

🕓10-second takeaway
Restrictive transfusion strategies for anemia are now accepted as an appropriate treatment for most critically ill patients, but the best transfusion strategy for minimizing neurological injury in traumatic brain injury (TBI) remains unclear. In this multicenter, international randomized trial, a liberal transfusion strategy did not significantly reduce the risk of unfavorable outcomes in ICU patients with a moderate or severe TBI at 6 months compared to a restrictive transfusion strategy. However, a liberal transfusion strategy was associated with better scores on some quality of life measures. A restrictive transfusion strategy for managing anemia in patients with a TBI may be appropriate, but further research is needed to assess the impact on nuanced measures of neurological recovery.

🔹Original study
Turgeon AF, Fergusson DA, Clayton L, et al. Liberal or restrictive transfusion strategy in patients with traumatic brain injury. N Engl J Med, 2024. doi: 10.1056/NEJMoa2404360

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💠One-Minute Telegram | #106, September 2024
❕The One-Minute Telegram is a journal club for busy doctors, with the latest research distilled down to just one minute.

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✍️Medical editors
•  J. Jan, MD
•  R. von Simson, MBBS, MSc, DLSTHM, MRCEM
Copy editor
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⏰#3: Blind dating with AI: predicting gestational age

🕓10-second takeaway
Ultrasound is a key tool used in comprehensive prenatal care assessments and allows for estimation of gestational age (GA). However, health care providers in many resource-limited settings lack the training necessary for accurate interpretation. In this prospective diagnostic accuracy study, a low-cost point-of-care AI tool allowed novice ultrasound users to estimate GA between 14 and 27 weeks’ gestation as accurately as credentialed sonographers. AI-powered ultrasound could substantially increase the availability of accurate GA estimation in low-resource settings.

🔻Original study
Stringer JSA, Pokaprakarn T, Prieto JC, et al. Diagnostic accuracy of an integrated AI tool to estimate gestational age from blind ultrasound sweeps. JAMA, 2024. doi: 10.1001/jama.2024.10770

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